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. 2003 May 5;197(9):1107–1117. doi: 10.1084/jem.20021787

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Copyright © 2003, The Rockefeller University Press

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Figure 2. — Dectin-1 and TLR2 collaborate in zymosan recognition by HEK 293 cells. (a and b) Activation of NF-κB (ELAM luciferase) was measured in HEK 293 cells transiently transfected with the indicated expression vectors and stimulated with 100 μg/ml zymosan or 100 ng/ml PAM₃CSK₄ lipopeptide for 4 h. (c) Activation of NF-κB was measured in HEK 293 cells transfected with expression vectors for TLR2 (together with either CD14 or dectin-1) and stimulated with 100 μg/ml zymosan in the indicated concentrations of laminarin.