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. 2003 May 5;197(9):1107–1117. doi: 10.1084/jem.20021787

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Copyright © 2003, The Rockefeller University Press

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Figure 5. — TLRs and dectin-1 collaborate in primary bone marrow dendritic cells. (a) Induction of cytokines in mouse BMDCs was measured by ELISA. The cells were stimulated for 4 h with 100 μg/ml zymosan or 100 ng/ml PAM₃CSK₄ lipopeptide in the presence or absence of 500 μg/ml laminarin. N.D., none detected. (b) Induction of cytokines was measured by quantitative real-time PCR in primary dendritic cells from MyD88^+/+ and MyD88^−/− mice stimulated for 4 h as in a. (c) Induction of IL-12 p40 was measured by quantitative real-time PCR in dendritic cells from Mac-1(CD11b)^−/− mice stimulated as in b.