Figure 4.
In situ hybridization analysis of lymphoid chemokine transcription in LN and RIPLTαβ pancreas. C57BL/6 PLN (A, C, and E) and serial sections of RIPLTαβ pancreas (B, D, and F) were probed with DIG-labeled antisense CCL21 (A and B), CCL19 (C and D), and CXCL13 (E and F) riboprobes. Positive signal is seen as dark purple staining. Arrows in A and B denote high magnification inset. I, Islet.