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. 2003 May 5;197(9):1153–1163. doi: 10.1084/jem.20021761

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Copyright © 2003, The Rockefeller University Press

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Figure 5. — LTαβ contributes to luminal PNAd expression on HEV. PNAd expression was detected by immunohistochemistry analysis with MECA 79 antibody in C57BL/6 PLN (A and B), RIPLTα pancreas (C and D), RIPLTαβ pancreas (E and F), and LTβ^−/− MLN (G and H). LTβ^−/− MLN exhibited a reduction in luminal MECA 79 expression. RIPLTαβ pancreata exhibited an increase in the number of MECA 79⁺ vessels and in luminal PNAd expression compared with the predominately abluminal pattern observed in RIPLTα pancreatic infiltrates. Objective 20× (A, C, E, and G); objective 40× (B, D, F, and H).