Table I.
FACS® Analysis of Lymphoid Cells from Bcl-xγ−/− and Bcl-xγ Tg Mice
| Thymus | Bcl-xγ wt | Bcl-xγ2/− | Bcl-xγ Tg |
|---|---|---|---|
| % | |||
| DN | 2.7 | 1.9 | 2.4 |
| DP | 82.1 | 86.5 | 85.3 |
| CD4 SP | 11.5 | 8.2 | 9.7 |
| CD8 SP | 3.8 | 3.4 | 2.6 |
| TCR-β+ | 18 | 17.5 | 19.4 |
| CD3+ | 14.4 | 12.7 | 19.7 |
| HAS+ | 90.3 | 92.4 | 93.2 |
| CD69+ | 15.6 | 14.1 | 13.4 |
| Spleen (%) | |||
| CD4 T cell | 60.3 | 62.8 | 62.1 |
| CD8 T cell | 30.7 | 27.2 | 31.2 |
| DN T cell | 9 | 9.5 | 6.7 |
| CD19/B220 | 28.2 | 29.6 | 27.7 |
| B220/CD8 | 6.4 | 6.4 | 7.8 |
| NK1.1 | 1.2 | 1.1 | 1.1 |
| TCR-β+ | 56.2 | 58.5 | 61.2 |
| TCR-γ+ | 0.6 | 0.7 | 0.4 |
| LN (%) | |||
| CD4 T cell | 64.9 | 60.9 | 64 |
| CD8 T cell | 32.7 | 36.3 | 33.4 |
| DN T cell | 2.5 | 2.8 | 2.3 |
| CD19/B220 | 8.8 | 10.1 | 9.7 |
| B220/CD8 | 1.9 | 1.5 | 1.4 |
| NK1.1 | 1.5 | 1.2 | 0.8 |
| TCR-β | 87.9 | 87 | 91.2 |
| TCR-γ | 0.8 | 0.6 | 0.5 |
Data shown are representative of one of three independent experiments with groups of three to four mice (8–12 wk of age).