Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2002 Jul 1;196(1):51–63. doi: 10.1084/jem.20020068

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2002, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 5. — Role of Cbl-b on Btk-dependent Ca²⁺ mobilization, IP₃ production, and tyrosine phosphorylation of PLC-γ2. Wild-type cells, Cbl-b–deficient cells, wild-type cells expressing T7-tagged Btk (C38-9 and C38-11), and Cbl-b–deficient cells expressing T7-tagged Btk (C37-4 and C37-10) were analyzed for (A) BCR-induced Ca²⁺ mobilization, (B) IP₃ production, and (C) tyrosine phosphorylation of PLC-γ2, as described in Fig. 2. Similar results were obtained using two other Cbl-b–deficient clones. All experiments were performed more than three times.