Figure 4.

LACK Ag-presenting capacity of CD11c⁺ DC subsets isolated directly from LNs after immunization. Sorted CD11c⁺CD8⁺, CD11c⁺CD8⁻B220⁻, and CD11c⁺CD8⁻B220⁺ (10⁴ cells) were cultured with LMR 7.5 cells (10⁵) for 24 h with or without LACK peptide (10 μg/ml) and IL-2 content assessed. Results are expressed as geometric mean ± SEM. * indicates P < 0.05 from CD11c⁺CD8⁺ and CD8⁻ as compared with that from CD11c⁺B220⁺ DCs.