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. 2002 Nov 4;196(9):1127–1140. doi: 10.1084/jem.20011247

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Copyright © 2002, The Rockefeller University Press

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Figure 6. — PBR expression augments the protective effects of myxoma virus infection. Jurkat or Jurkat-PBR cells were mock-infected (mock) or infected with myxoma virus (Myx) or the M11L knockout virus (M11L⁻). The percentage of cells that underwent a loss of TMRE fluorescence as a result of staurosporine treatment (A) or Fas stimulation (B) is shown. Results are the average of three independent experiments (±SD). In parallel, Jurkat or Jurkat-PBR cells that had been mock- or virus-infected were analyzed for the presence of M11L using immunoprecipitation and immunoblotting (C, top panel). Alternatively, virus infection was verified by the production of the early viral protein, M-T7 (C, bottom panel).