Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2003 Dec 15;198(12):1785–1796. doi: 10.1084/jem.20021562

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2003, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — IL-4 reconstitutes early and late CS responses in NKT cell–deficient mice. (A) WT 1-d PCl immune mice (Group A) were compared with 1-d immune CD1d^−/− mice (Group B) as recipients of 4-d PCl immune T cells from CD1d^+/+ mice. WT immune mice elicited 2 and 24 h CS (Group A), whereas the CD1d^−/− mice did not (Group B). Groups C–E are identical to Group B. However, these 1-d immune CD1d^−/− mice that received isolated immune T cells also were injected with different doses of rIL-4 during immunization. *P < 0.05; **P < 0.001. (B) WT BALB/c 1-d active PCl immune mice (Group B) were compared with 1-d immune Jα18^−/− (Group C) as recipients of 4-d PCl immune magnetic-separated T cells from BALB/c mice. Group D is identical to Group C, but 20 ng i.v. of IL-4 was injected during immunization of the 1-d immune Jα18^−/− recipient mice. In A and B, the results are mean ± SE from four mice per group.

Figure 7. — IL-4 reconstitutes early and late CS responses in NKT cell–deficient mice. (A) WT 1-d PCl immune mice (Group A) were compared with 1-d immune CD1d^−/− mice (Group B) as recipients of 4-d PCl immune T cells from CD1d^+/+ mice. WT immune mice elicited 2 and 24 h CS (Group A), whereas the CD1d^−/− mice did not (Group B). Groups C–E are identical to Group B. However, these 1-d immune CD1d^−/− mice that received isolated immune T cells also were injected with different doses of rIL-4 during immunization. *P < 0.05; **P < 0.001. (B) WT BALB/c 1-d active PCl immune mice (Group B) were compared with 1-d immune Jα18^−/− (Group C) as recipients of 4-d PCl immune magnetic-separated T cells from BALB/c mice. Group D is identical to Group C, but 20 ng i.v. of IL-4 was injected during immunization of the 1-d immune Jα18^−/− recipient mice. In A and B, the results are mean ± SE from four mice per group.