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. 2003 Dec 15;198(12):1785–1796. doi: 10.1084/jem.20021562

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Copyright © 2003, The Rockefeller University Press

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Figure 8. — Immune B-1 cells from CD1d^+/+ mice reconstitute 2 and 24 h CS in PCl-sensitized CD1d^−/− mice. WT CD1d^+/+ controls (Group A) and CD1d^−/− mice (Groups B–D) were contact sensitized. Then, 3 d later Group C received 1-d immune cells from CD1d^+/+ mice, and Group D received sorted 1-d immune CD19⁺CD5⁺ B-1 cells from CD1d^+/+ mice. On day 4, all groups were ear challenged. Nonimmune CD1d^−/− mice (Group E) and CD1d^+/+ mice (Group F) were also ear challenged. Group G is nonimmune WT mice that just received 1-d PCl immune cells. Ear swelling was measured at 2 and 24 h, and the results are from a representative experiment with four mice per group; *P < 0.05; **P < 0.01.