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. 2003 Aug 18;198(4):591–602. doi: 10.1084/jem.20022042

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Copyright © 2003, The Rockefeller University Press

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Figure 4. — mIgM(P436S) mice generate smaller and fewer GCs throughout most of the primary immune response. Spleens were frozen from each experiment and 5 μm frozen sections were cut and stained with anti λ-AP (blue) and PNA-bi/SA-HRP (red). mIgM spleens consistently show more GCs of larger size than mIgM(P436S) spleens.