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. 2003 Oct 6;198(7):1119–1126. doi: 10.1084/jem.20030411

Table III.

Persistence of Bim-deficient HEL-binding B Cells in the Presence of Soluble Self-antigen

Donora
Recipientb
Cellularityc
IgDa+
IgDa+ d
HEL bindingd
(n) 106 % of organ 106 106
Tg+ bim+/+ Control (3) 29.3 ± 9.5 55.9 ± 2.3 16.4 ± 5.6 15.0 ± 4.7
sHEL+ (3) 8.1 ± 3.1 17.3 ± 7.5 1.4 ± 0.9e 1.2 ± 0.9f
Tg+ bim−/− Control (3) 51.5 ± 17.3 51.8 ± 12.3 26.7 ± 14.6 23.3 ± 14.7
sHEL+ (3) 86.7 ± 54.3 29.3 ± 11.4 25.4 ± 13.8e 20.2 ± 13.9f
a

Genotype of bone marrow donor used in original reconstitution.

b

Recipients were either C57Bl/6 (control) or C57Bl/6 sHEL transgene positive.

c

Cellularity is as defined in Table I.

d

IgDa and HEL-binding counts are as determined for Table I.

e

P < 0.05.

f

P = 0.07.