Table I.
Characteristics of H. pylori cagY MRR Direct DNA Repeat Sequences and Their Recombination Potential a
Repeat sequencesb
|
Recombination potentialc
|
||||
---|---|---|---|---|---|
H. pylori strain | Total number(independent) | Mean ± SDcopies | Mean ± SD size(bp) | Number ofregionsd | Range in fragment size (bp) |
26695 | 302 (99) | 3.1 ± 1.6 | 36.1 ± 22.8 | 443 | 111–2,187 |
J99 | 235 (78) | 3.0 ± 1.7 | 48.2 ± 42.7 | 347 | 114–2,205 |
NCTC11638 | 255 (82) | 3.1 ± 2.0 | 34.9 ± 23.5 | 425 | 114–2,544 |
The MRR of cagY in the three strains are shown in Fig. 1.
≥16 nucleotides (refer to Materials and Methods).
Recombination potential defined as number of regions flanked by direct DNA repeats, and fragment size as intervening segment plus one repeat.
All potential recombination events involving the 1,215 regions identified (leading to either DNA deletion or duplication) result in in-frame ORF (P < 0.001).