Table 4.
Polygenic Variance | Major Locus Variance | Additive Effect (a) | Dominance Deviation (d) | τAAb | τAB | τBB | Frequency (q) | |
General Major Locus, Mendelian Transmission | ||||||||
Mean | 1.48 | 8.46 | 3.64 | -2.65 | 1.0 | 0.5 | 0.0 | 0.84 |
Median | 1.53 | 9.72 | 3.89 | -2.57 | - | - | - | 0.83 |
SD | 0.84 | 10.21 | 1.18 | 1.35 | - | - | - | 0.11 |
Eff Sample Sizec | 1417.3 | 1007.3 | 980.2 | 1013.6 | - | - | - | 1198.6 |
Conv Score (p)d | 1.32 (0.19) | 1.55 (0.12) | 1.68 (0.09) | 1.71 (0.09) | - | - | - | 1.49 (0.14) |
HDRe 95% Low | 0.00 | 0.00 | 1.48 | -5.21 | - | - | - | 0.38 |
HDR 95% High | 3.22 | 33.14 | 7.77 | 0.06 | - | - | - | 1.00 |
Recessive Major Model, Mendelian Transmission | ||||||||
Mean | 2.21 | 13.19 | 3.68 | -3.68 | 1.0 | 0.5 | 0.0 | 0.74 |
Median | 2.33 | 12.32 | 3.65 | -3.65 | - | - | - | 0.75 |
SD | 0.60 | 6.03 | 0.84 | 0.84 | - | - | - | 0.41 |
Eff Sample Size | 1330.9 | 1121.0 | 1032.6 | 1032.6 | - | - | - | 1064.1 |
Conv Score (p) | -1.27 (0.20) | 1.51 (0.13) | 1.74 (0.08) | 1.74 (0.08) | - | - | - | 1.42 (0.16) |
HDR 95% Low | 0.39 | 0.00 | 2.15 | -6.23 | - | - | - | 0.44 |
HDR 95% High | 3.16 | 45.89 | 7.42 | -1.03 | - | - | - | 1.00 |
General Major Locus, Non-Mendelian Transmission | ||||||||
Mean | 1.46 | 6.53 | 4.13 | -3.01 | 0.63 | 0.52 | 0.18 | 0.94 |
Median | 1.57 | 6.34 | 4.36 | -3.29 | 0.70 | 0.51 | 0.01 | 0.99 |
SD | 0.88 | 8.18 | 1.62 | 1.57 | 0.05 | 0.05 | 0.13 | 0.03 |
Eff Sample Size | 1387.6 | 1109.2 | 1290.3 | 1088.1 | 1172 | 1043 | 941 | 1186.4 |
Conv Score (p) | 1.18 (0.24) | 1.40 (0.16) | 1.37 (0.17) | 1.19 (0.23) | 1.08 (.28) | 1.19 (.23) | 1.75 (.08) | 0.97 (0.33) |
HDR 95% Low | 0.00 | 0.00 | 0.53 | -7.11 | 0.52 | 0.26 | 0.00 | 0.75 |
HDR 95% High | 3.23 | 33.69 | 8.04 | -0.48 | 0.86 | 0.66 | 0.63 | 1.00 |
a Estimates are taken from a Gibbs sample of 9,000 values.
b Mendelian transmission parameter; the probability of transmitting an "A" allele. For Mendelian transmission these values are fixed as 1.0, .50 and 0.0 for putative major genotypes AA, AB and BB, respectively. Non-Mendelian transmission implies estimation of these values from the data.
c Effective sample size.
d Gibbs sample convergence statistic; Geweke (1992).
e Highest density region