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Down-regulation of the hepatic Fetuin-A mRNA level in LPS-challenged mice. The Fetuin-A mRNA level was measured by real-time Q-RT–PCR at 24 or 48 h post-challenge in mice given either LPS in an aqueous NaCl solution (n = 4) or the vehicle alone as a control (n = 3). At each time point, the LPS-induced mRNA levels are relative to the average level in mice given the vehicle alone.
