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Airway responsiveness to increasing concentrations of methacholine at various points after inoculation of mice with saline (open bars) or C. pneumoniae (black bars). A: Day 2; B: Day 7; C: Day 14, D: Day 21. (*p < 0.05; **p < 0.001; ***p < 0.005, n = 7–8). Unrestrained plethysmograph measurements were performed for 3 min after each exposure to methacholine and expressed as Penh-values.
