Figure 5.
Power comparison for different topologies. (A) Topologies considered. Topologies in the same row have the same total branch length and same number of comparative genomes. Each column corresponds to a class of topologies. One unit branch length is 0.196199 substitutions per site (mouse-rat like). The number of comparative genomes is equal to the number of units. For topologies with balanced branch lengths, all branches have the same length. For topologies with unbalanced branch lengths, all branches except the long branch have length equal to 0.02 substitutions per site. The length of the long branch is set to make the total branch length equal to 8 units. (B) Corresponding ROC curves. As illustrated in the legend, the different groups of curves represent different topology classes. Different point groups highlighted along the curves represent the different rows in Figure 5(A). The locations of these points correspond to a posterior probability threshold equal to 0.5. The crosses show the 1st-to-3rd quartile range of the sensitivity and specificity.