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. Author manuscript; available in PMC: 2008 Nov 1.
Published in final edited form as: Exp Eye Res. 2007 Aug 8;85(5):678–683. doi: 10.1016/j.exer.2007.08.001

Figure 1. Staurosporine-induced differentiation of RGC-5 cells increases MAP2c expression.

Figure 1

(A) RGC-5 cells differentiated in the presence of 316 nM staurosporine (SS) for 3 days showed roughly equal levels of MAP2a and MAP2b compared to undifferentiated (0 nM SS) RGC-5 cells. However, levels of the low molecular weight isoform, MAP2c, showed increased expression. (B) MAP2c expression in undifferentiated cells is more evident at longer exposure times, although MAP2a and MAP2b tend to be overexposed at these times (bands shown are from a separate experiment than in A). (C) Quantitation of band strength demonstrated that the increase was 2- to 16-fold after differentiation (6.5 ± 2.4).