TABLE 1.
Group | Cytokine production (mean ± SD)a
|
|||
---|---|---|---|---|
IL-2 (pg/ml) | IFN-γ (ng/ml) | IL-4 (pg/ml) | IL-10 (pg/ml) | |
pcDNA3 | 27 ± 9 | 10 ± 1.3 | 29 ± 10 | 281 ± 167 |
pMIC3i | 210 ± 45 | 11.5 ± 0.3 | 32 ± 14 | 332 ± 228 |
pMIC3i plus pGM-CSF | 242 ± 57 | 111.9 ± 11 | 33 ± 10 | 343 ± 226 |
Cell-free supernatants were harvested and assyed for IL-2 and IL-4 activities at 24 h, IL-10 activity at 72 h, and IFN-γ activity at 96 h.