Table 1.

Cytokine Secretion by Purified T Cell Populations from SEA-treated versus PBS-treated B10.A TCR–Cyt 5C.C7-1 Rag-2^−/− Mice

	CD4+ T cells		CD8+ T cells
	PBS-treated	SEA-treated	PBS-treated	SEA-treated
IL-10 (pg/ml)	50	1,500	25	100
TGF-β (pg/ml)	n.d.	30	n.d.	n.d.
TGF-β (acid-activated, pg/ml)	n.d.	400	n.d.	n.d.
IL-4 (pg/ml)	n.d.	n.d.	n.d.	n.d.
IL-2 (U/ml)	94	0.06	72	0.05
IFN-γ (U/ml)	>10	1.25	>10	1.25

FACS^®-sorted CD4⁺ or CD8⁺ T cells were stimulated for 48 h in the presence of PCC 81–104 peptide plus APCs. The supernatants were then removed and measured for cytokine production by bioassay (for determination of units/milliliter IL-2) or ELISA. Data are representative of three separate experiments. n.d., not detectable.