Table 2.
Short-lived | Long-lived | Short→long-lived | |
---|---|---|---|
Control | 5.6 (100%) | 29.4 (100%) | 0.9 (100%) |
CD45−/− | 37.8 (670%) | 46.2 (157%) | 0.8 (89%) |
CBA/N | 5.2 (92%) | 4.8 (16%) | 0.1 (11%) |
The absolute number (× 106) of labeled (short-lived) and unlabeled (long-lived) B cells in the spleens of control, CD45−/−, and CBA/N mice was calculated after 3 d of continuous treatment with BrdU. The number of labeled B cells detected 18 d after the 3-d BrdU treatment period corresponds to the number of B cells that became long lived. Numbers of labeled and unlabeled B cells in mutant mice are given in parentheses as percentages of the numbers found in control mice .