Figure 1.

Enhancement of RANTES- and SDF-1α–induced chemotaxis by TCS in THP-1 cells. Cells were challenged with RANTES (RAN, A) or SDF-1α (SDF, B) at concentrations indicated in the presence or absence of 2 nM TCS at 37°C for 3 h, and the chemotaxis was determined as described in Materials and Methods. THP-1 cells were incubated with different concentrations of TCS (C) in the absence or presence of 1 nM RANTES or 1 nM SDF-1α at 37°C for 3 h, and the migrated cells were collected and counted as described above. Data were mean ± SE of two independent experiments performed in duplicate.