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. 1999 Jul 19;190(2):229–240. doi: 10.1084/jem.190.2.229

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© 1999 The Rockefeller University Press

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IL-10 is produced only by PP DCs after CD40L trimer stimulation, whereas similar levels of IL-12 p40 is detected from both DC types. FACS^®-purified CD11c⁺ DCs (10⁵ per well) from BALB/c (A and B) or B10.A (C and D) mice were incubated overnight in the presence of CD40L trimer (10 μg/ml). Supernatants were collected and IL-10 (A and C) and IL-12 p40 (B and D) levels were measured by ELISA. Each column is representative of four (A and B) or two (C and D) separate experiments.

IL-10 is produced only by PP DCs after CD40L trimer stimulation, whereas similar levels of IL-12 p40 is detected from both DC types. FACS^®-purified CD11c⁺ DCs (10⁵ per well) from BALB/c (A and B) or B10.A (C and D) mice were incubated overnight in the presence of CD40L trimer (10 μg/ml). Supernatants were collected and IL-10 (A and C) and IL-12 p40 (B and D) levels were measured by ELISA. Each column is representative of four (A and B) or two (C and D) separate experiments.