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. 1999 Aug 2;190(3):385–398. doi: 10.1084/jem.190.3.385

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© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Histopathological assessment of arthritic joints. Mice treated with mGAL-1–transfected fibroblasts (4 × 10⁶ cells/mouse) showed mainly normal joints (A) and some moderately arthritic joints (B). Control mice treated with pCDNA3-transfected cells (4 × 10⁶ cells/mouse) showed moderate (B) and severe arthritis (C) accompanied by synovitis, erosions, and loss of joint integrity. A–C, hematoxylin and eosin staining; original magnification: ×100. Percentage of histological score per group is shown in D.