Figure 4.

Blood glucose levels in A18 × BDC2.5 dual TCR mice that were either immunized with C5 protein or peptide (•) or treated with PBS or CFA alone (○). Immunization took place at 4–6 wk of age. Each circle represents a single mouse, and circles are spaced in four columns for each month of age to make it easier to follow the development of individual mice. For the last time point at 5 mo, not all mice were still available, as a proportion of mice had been killed for in vitro experiments.