Table 2.

EAE in Wild-type and B7-1/B7-2^−/− Mice Induced by Adoptive Transfer of Wild-type MOG-specific T Cells

	Clinical EAE				Histological EAE
	Incidence	Day of onset	Mean maximal score	Duration (d)	Incidence	Meningeal foci	Parenchymal foci	Total foci
		mean ± SE	mean ± SE	mean ± SE		mean ± SE	mean ± SE	mean ± SE
Wild-type	10/16				14/16
	(62.5%)	12.0 ± 0.8	2.5 ± 0.2	19.0 ± 1.0	(87.5%)	40.3 ± 9.0	32.9 ± 8.9	76.3 ± 9.4
B7-1/B7-2−/−	8/13	16.0 ± 1.7	1.3 ± 0.1	8.5 ± 1.5	11/13	11.4 ± 3.3	2.2 ± 0.7	13.6 ± 3.8
	(61.5%)	P < 0.05	P < 0.001	P < 0.001	(84.6%)	P < 0.001	P < 0.01	P < 0.001