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IEL Subsets of Normal and Mutant Mice
| Mice | No. IELs/100 ECs | TCR-α/β | TCR-γ/δ | ||
|---|---|---|---|---|---|
| CD8α/α | CD8α/β | CD4+8− | |||
| Controls (n = 27) | 14 (3) | 20 (10) | 7 (4) | 2 (2) | 59 (8) |
| KbDb KO (n = 9) | 14 (3) | 28 (10) | 0.6 (0.4) | 2 (1) | 60 (4) |
| CD1 KO (n = 6) | 13 (2) | 17 (5) | 12 (8) | 1 (1) | 51 (9) |
| TAP KO (n = 6) | 13 (3) | 10 (7) | 0.5 (0.4) | 2 (1) | 80 (7) |
| β2m KO (n = 7) | 10 (3) | 1.4 (1.1) | 0.1 (0.1) | 1.1 (0.3) | 90 (3) |
