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. 1999 Oct 18;190(8):1081–1092. doi: 10.1084/jem.190.8.1081

Table 4.

Increased Stability of the IFN-γ1 IL-4− Phenotype in Subclone Families Derived from Activated Cells

Cells IL-2 IL-2 + IL-4
IFN-γ1 IL-4− IFN-γ1 IL-4− IFN-γ2 IL-4− IFN-γ2 IL-4+ IFN-γ1 IL-4+
Normal LNlow 56 12 0 3 41
Influenza lunglow 47 27 2 0 18
Influenza lunghigh 55 43 1 0 11

The table shows the breakdown of cytokine phenotypes among subclones grown with IL-2 + IL-4 in those families where subclones grown in IL-2 alone displayed a IFN-γ1 IL-4− phenotype. These families represent 60, 66, and 74%, respectively, of all normal LNlow, influenza lunglow, and influenza lunghigh families analyzed. Data shown as number of subclone families.