. 1999 Nov 15;190(10):1439–1450. doi: 10.1084/jem.190.10.1439

Table 1.

Coexpression of Cytokines in Individual Cells in Correlation with Proliferation

		Cell generation
		0	1	2	3	4	5	6	7	8	9	Total
IL-2/IL-4	Day 2	0.07	0.06	0.14								0.04
	Day 3			0.01	0.07	0.07	0.07					0.03
	Day 4					0.08	0.10	0.04	0.06			0.04
	Day 5						0.24	0.18	0.18	0.15		0.13
	Day 6							0.28	0.24	0.27	0.23	0.23
IL-4/IL-10	Day 3			0.10	0.11	0.15	0.08					0.11
	Day 4					0.24	0.25	0.24	0.22			0.23
	Day 5						0.30	0.39	0.38	0.37		0.34
	Day 6							0.21	0.24	0.27	0.22	0.26
IL-2/IL-10	Day 4					0.04	0.00	0.04	0.02			0.02
	Day 5						0.00	0.12	0.14	0.09		0.06
	Day 6							0.06	0.06	0.08	0.04	0.06

CFSE-labeled, naive CD62L⁺CD4⁺ OVA-TCR^tg/tg cells were activated with OVA_323–339 and APCs in the presence of IL-4, anti–IL-12, and anti–IFN-γ. From day 2 to day 6, samples were restimulated and analyzed for the simultaneous expression of IL-2 and IL-4, IL-4 and IL-10, and IL-2 and IL-10 in individual cell generations and in the total cell population of OVA-TCR⁺ cells. Phi (φ) correlation coefficients are given.