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IgG GMT (A) and SBA titers (B) against six PorAs after immunization with HexaMen (open bars), HexaMix (solid bars), and homologous monovalent OMVs (dotted bars). ELISA plates were coated with PorB/Rmp-negative OMVs consisting of 85 to 94% PorA. The error bars indicate the standard errors of the means. Asterisks indicate significant differences in PorA-specific titers following the different types of immunization (P ≤ 0.05).
