Table 2.

Increased MHC Class II Expression on B Cells and Enlarged Proportion of MZ B Cells in the Spleen of BAFF-Tg Mice

		Levels of MHC class II expression on B220+ B cells (MFI)	Percentage of follicular B cells*	Percentage of MZ B cells‡	Percentage of newly formed B cells§
Control mice
	816-1-10	1170	45	6	12
	802-21	1029	48	10.5	9
	823-1	1240	39	9	6.5
BAFF-Tg mice
	802-6	1707	49	18	5.9
	820-7	1900	39	23	6.3
	816-1-1	2088	40	23	5.8

Splenocytes were analyzed by FACS^® and gated on the B220⁺ population. A representative experiment is shown. MFI, mean of fluorescence intensity.

*B220⁺/ΙγΜ^lo/CD21^int.

^‡B220⁺/IgM^hi/CD21^hi.

^§B220⁺/IgM^hi/CD21^lo.