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. 2000 Jan 17;191(2):375–380. doi: 10.1084/jem.191.2.375

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Effect of anti-OX40L mAb treatment on serum IgG Ab and IgE in L. major–infected BALB/c mice. (A) Serum total IgG 40 d after infection was measured by sandwich ELISA. Results are expressed as mean ± SD of six mice in each group. (B) L. major–specific IgG Ab isotypes were determined with serum 40 d after infection against SLAs by isotype-specific ELISA. Data represent OD obtained at a 500-fold dilution of serum and are expressed as mean ± SD of six mice in each group. (C) Serum IgE at 14, 30, and 40 d after infection was measured by IgE-specific sandwich ELISA. Results are expressed as mean ± SD of six mice in each group. Significant differences between control IgG and anti-OX40L mAb treatment are indicated by asterisks (*P < 0.05; **P < 0.01). Similar results were obtained in two independent experiments.