Table 1.

Summary of V_H186.2 Sequences from NP-specific IgG1⁺ B Cells at Day 42 after Immunization

	Control CD38+	bcl-2 CD38+
Single cells	74	38
PCR+	31	32
VH186.2+	26	24
R/S ratio
CDR1+2	4.0	2.9
FW1−3	2.7	1.8
Position 33 W→L	62%	13%
Mutation average	4.6	2.7
Range	0–14	0–12

R/S ratio, ratio of replacement to silent mutations.