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. 2000 Mar 6;191(5):813–822. doi: 10.1084/jem.191.5.813

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Reconstitution of W/W^v mice with BMMCs restores EAE disease onset and severity to wild-type levels. (A) Clinical scores were assigned daily to wild-type (n = 10), W/W^v (n = 8), and W/W^v + BMMCs (n = 12) mice, and the mean of each group was reported (P < 0.0001; post-test results comparing W/W^v to wild-type or W/W^v to reconstituted group: P < 0.001). Repeated measures of ANOVA followed by the Bonferroni post-test was used for comparison of the mean clinical scores of the three groups in the reconstitution experiments. (B) Graph represents the percent of total animals who demonstrated disease by day 30 after immunization (P < 0.004). Curve was plotted according to the method of Kaplan-Meier, and significance was calculated by the log-rank test. Results from A and B represent cumulative data from two independent experiments.