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Phosphorylation of Akt and MAPK after BCR stimulation of purified B cells. Western blot analysis showing the time course of Akt (Akt-P) and MAPK (p44-P and p42-P) phosphorylation in wild-type (+/+) and knockout (−/−) B cells after BCR stimulation with the F(ab′)2 (left) or intact (right) goat anti–mouse IgM. Protein levels of Akt and MAPK are shown to indicate relative expression levels.
