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. 2000 Oct 16;192(8):1151–1164. doi: 10.1084/jem.192.8.1151

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© 2000 The Rockefeller University Press

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graphic file with name JEM000726.f7a.jpg — Representative examples of V_H diversification occurring in the B cell clones that exhibit V_H replacements. In each instance (A, B, and C), the identified cDNA clones are represented by filled circles and the presumed (unidentified) clones are represented by hashed circles. The numbers of mutations are contained within the circles and their locations (FR vs. CDR) and types (replacement [R] vs. silent [S]) are displayed adjacent to the circles.

graphic file with name JEM000726.f7b.jpg — Representative examples of V_H diversification occurring in the B cell clones that exhibit V_H replacements. In each instance (A, B, and C), the identified cDNA clones are represented by filled circles and the presumed (unidentified) clones are represented by hashed circles. The numbers of mutations are contained within the circles and their locations (FR vs. CDR) and types (replacement [R] vs. silent [S]) are displayed adjacent to the circles.