Figure 3.

Transfer of OT1 cells does not cause accelerated clearance of VV-ova. B6.PL mice with or without transfer of 10⁶ B6 OT1 transgenic T cells were immunized with VV-ova as in the legend to Fig. 1. On days 5 and 7 after infection, viral plaque assays were performed on pooled spleen and ovary tissue. The data shown are from triplicate titers of triplicate mice per time point. As a control, a small number of T cells were stained with tetramer from the transferred group of mice to insure that the transferred cells had indeed responded to the viral challenge (data not shown).