Figure 5.
Lysis of PRAME transfected renal cell carcinoma cell line MZ1851 by CTL anti-PRA300–309. CTL no. 460 directed against PRA300–309 was tested on 51Cr-labeled MZ1851 (HLA-A*0201+ but lacking PRAME expression) transfected with PRAME cDNA (▴) vs. MZ1851 transfected with the empty vector (•). CTL no. 460 was used at E/T ratios ranging from 50 to 0.75. Results of one representative experiment of three performed are shown.