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. Author manuscript; available in PMC: 2008 Jan 14.
Published in final edited form as: J Am Chem Soc. 2006 Apr 19;128(15):4992–5000. doi: 10.1021/ja056613z

Figure 5.

Figure 5

Analysis of wild-type telomerase processivity by a direct radioactivity based assay. (A) Gel showing bands representing the extension products of the telomerase reaction. (B) Result of fitting the gel data based on the function y = AXn-1, where A is the intensity of the first band, n is the number of repeats added for a given band in the gel, and X is the mean processivity of the enzyme as defined in the data analysis section. Intensities from each band in (A) were divided by the number of repeats in the extended products to normalize for the number of equivalents of radioactivity incorporated. The mean processivity derived from the fit is 0.37 ± 0.01.