Table 1.

Histopathological Assessment of EAE in MBP-immunized B6,129 Mice

Genotype	Mean week (range)	Inflammation (%)	Demyelination (%)
B6,129.TNF−/−	11.6 (9–15)	7/10 (70)	2/10 (20)
B6,129	11.7 (9–15)	0/8 (0)	0/8 (0)
B6,129.p55−/−	11.3 (9–12)	0/9 (0)	0/9 (0)
B6,129.p55p75−/−	12.5 (9–15)	2/6 (33)	1/6 (17)

Sections throughout the spinal cord of the immunized mice were stained with luxol fast blue and nuclear fast red. The presence of inflammation and demyelination was assayed qualitatively in 30–50 sections per mouse.