. 2001 Feb 5;193(3):329–338. doi: 10.1084/jem.193.3.329

Table 1.

AND TCR Transgenic T Cells Are Not Spontaneously Activated In Vivo

	Percentage CD25⁺	Percentage CD69⁺	Percentage activated
Young B10.AND	1.7	2.1	1.6
Young CBA.AND	2.0	1.0	1.9
Young MRL.AND	1.7	1.8	1.4
Older B10.AND	5.9	10.4	4.6
Older CBA.AND	3.3	5.3	6.8
Older MRL.AND	3.8	9.8	4.5

Flow cytometry was performed on CD4⁺Vα11^hi T cells for the activation markers CD69, CD25, CD44, and CD62L in both young (1–2 mo) and older (8–9 mo) AND TCR transgenic mice. Activated T cells were defined as the CD44^hi CD62L^lo population (reference 15). Results are representative of two separate experiments involving cohorts of two to three transgenic animals from each group (MRL.AND, B10.AND, and CBA.AND).