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Summary of Mouse Strains with Disrupted J Chain Locus
| JDTA | JcMyc | J−/− | |
|---|---|---|---|
| Serum Ig | − | +/− | +/− |
| Serum IgM | − | +/− | − |
| Serum IgG | − | +/− | +/− |
| Serum IgA | ++ | ++ | + |
| LP SFC | − | ND | +/− |
| BM SFC | − | +/− | − |
| Spleen SFC | − | + | − |
| Systemic IR | − | + | +/− |
| Gut | − | ND | − |
+, increased; −, decreased; +/−; unchanged; IR, immune response; and SFC, spot-forming cell.
