Figure 2.

Restoration of phenotype by expression of pTα transgenes. (A) CD4 versus CD8 expression on thymocytes from pTα^−/− (left) and p300ΔP.pTα^−/− (right). The percentage of thymocytes in each quadrant are shown. (B) The percentage of DP (i.e., CD4⁺CD8⁺) cells in the thymi of mice expressing different pTα transgenes. Individual vertical lines represent independent lines of mice; individual data points on those vertical lines represent the percentage of DP cells in the thymi of individual mice. (C and D) The percentage of DN γ/δ cells (C) or CD4⁺ γ/δ cells (D) in the thymi of mice expressing different pTα transgenes. Individual vertical lines represent independent lines of mice; individual data points on those vertical lines represent the percentage of γ/δ cells in the thymi of individual mice. (E) Total cellularity of the thymus (×10⁶ cells) was established by trypan blue exclusion. Individual vertical lines represent independent lines of mice; individual data points on those vertical lines represent the cell numbers in individual mice.