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Effect of Vpu and Vpr on Induction of Apoptosis in HIV-1–infected Jurkat Cells
| HIV-1 phenotype
|
% annexin V+ cells
|
||||
|---|---|---|---|---|---|
| Clones | vpr | vpu | env | Day 1 | Day 2 |
| Mock | 1.9 | 1.9 | |||
| NL43-K1 | + | + | − | 4.4 | 72.4 |
| NL43-K1/Udel | + | − | − | 3.0 | 39.4 |
| NL43-K1/U2/6 | + | ma | − | 4.1 | 44.9 |
| NL43-EcK1 | mb | + | − | 2.3 | 41.4 |
| NL43-Eck1/Udel | mb | − | − | 2.1 | 15.0 |
| NL43-Eck1/U2/6 | mb | ma | − | 2.3 | 20.2 |
Vpu2/6.
vpr-defective mutant.
