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. 2001 Feb 5;152(3):645–650. doi: 10.1083/jcb.152.3.645

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Gross appearance and skin morphology of mut^neo/mut^neo mice. (A) mut^neo/mut^neo pup shortly after birth with severe blistering and erosions. (B) Histological analysis of a skin biopsy from A shows a split in the suprabasal layer of the epidermis. Hematoxylin and eosin, bar = 50 μm. (C) Immunolabeling shows abundant mutant K10 (yellow) throughout the disintegrating suprabasal layer against the red K14 background stain. Bars = 50 μm.