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. 1997 Feb 3;185(3):415–428. doi: 10.1084/jem.185.3.415

Figure 6.

Figure 6

The induction of Th1-type (IFN-γ) and Th2-type (IL-5 and IL-10) cytokines in sera of mice receiving rmIL-12 and orally immunized with TT and CT as adjuvant. Mice received the combined oral vaccine (unshaded) together with rmIL-12 by the i.p. route (striped, 15 times, 100 ng/dose) or by the oral route (shaded six times, 1,000 ng/dose). Levels of IFN-γ, IL-5, and IL-10 in the serum were determined on day 21 by ELISA. The results are expressed as the mean ± one SD and are representative of three different experiments.