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. 2002 Aug 19;196(4):447–457. doi: 10.1084/jem.20020052

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Copyright © 2002, The Rockefeller University Press

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Figure 4. — Effect of kynurenine on T cell proliferation induced by allogeneic DCs or anti-CD3 antibody. Peripheral lymphocytes were stimulated with (A) allogeneic DCs or (B) anti-CD3 mAb for 6 and 3 d, respectively. Various amounts of kynurenine (abscissa) were added to the cultures. Positive control was performed without kynurenine. T cell proliferation was determined by ³[H]thymidine incorporation (cpm) (ordinate).