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. 2002 Aug 19;196(4):447–457. doi: 10.1084/jem.20020052

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Copyright © 2002, The Rockefeller University Press

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Figure 5. — Polyclonal restimulation of kynurenine-suppressed T cells. Peripheral lymphocytes were stimulated with (A) anti-CD3 mAb in the presence of various amounts of kynurenine (abscissa). Positive control consisted of T cell stimulation in the absence of kynurenine. After 2 d the cells were washed and (B) restimulated with Con-A for another 3 d. T cell proliferation was determined by ³[H]thymidine incorporation (cpm) (ordinate).