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. 2003 Jul 7;198(1):91–98. doi: 10.1084/jem.20030615

Figure 1.

Figure 1.

Impaired pre-B cell maturation in Btk-deficient, SLP-65-deficient, and Btk/SLP-65 double mutant mice. (A) Flow cytometric analysis of surface IgM/IgD expression on total lymphoid cells in the spleen. (B) Expression profiles of B220 and IgM on total lymphoid cells in the BM (top). The B220+IgM pro-/pre-B cell fraction was gated and analyzed for the indicated markers (bottom). Data are displayed as dot plots and the percentages of cells within the indicated quadrants or gates are given. Data shown are representative of four mice examined within each group.