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. 2003 Jul 7;198(1):39–50. doi: 10.1084/jem.20022235

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Copyright © 2003, The Rockefeller University Press

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Figure 6. — BrdU⁺ cells increased in the adnovirus-infected liver of PD-1^−/− mice. PD-1^−/− or WT mice (3 mice/group) were intravenously injected with Ad-lacZ. At day 0 (a) or day 7 (b) of infection, mice were intraperitoneally injected with BrdU 1 h before sacrifice. Splenocytes and intrahepatic lymphocytes were doubly stained for BrdU and CD19, CD3, CD4, or CD8. (c) The bars represent percentages of BrdU⁺ cells in the CD19, CD3, CD4, or CD8⁺ population at day 7 after infection. The results are representative of two separate experiments.